Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Rat Brain| Product Name | Rabbit anti-Bmp10 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Bmp10 |
| Immunogen | The immunogen for anti-Bmp10 antibody: synthetic peptide corresponding to a region of Rat |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Bmp10 |
|---|---|
| Gene Synonyms | Bmp10 |
| Gene Full Name | Bone morphogenetic protein 10 |
| Gene Summary | Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth. |
| Alternative Names | Bmp10 |
| Molecular Weight(MW) | 48kDa |
| Sequence | 421 amino acids |
| Entrez Gene | 500245 |
|---|---|
| SwissProt ID | Q4AEG6 |
| Protein Accession | NP_001026994 |
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Rat Brain| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
