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Rabbit anti-SDHB polyclonal antibody - middle region

Catalog Number:OM113075
OM113075
Discount Price
OM113075-100ul
1~2 Week
100ul
OM113075-50ul
50ul
OM113075-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-SDHB polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias IP, PGL4, SDH, SDH1, SDHIP, SDH2
Immunogen The immunogen for anti-SDHB antibody: synthetic peptide directed towards the middle region of human SDHB
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineGuinea PigHorseHumanMouseRabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SDHB
Gene Synonyms IP
PGL4
SDH
SDH1
SDHIP
SDH2
Gene Full Name Succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Gene Summary Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names IP
PGL4
SDH
SDH1
SDHIP
SDH2
Molecular Weight(MW) 31kDa
Sequence 280 amino acids
Database Links
Entrez Gene 6390
SwissProt ID P21912
Protein Accession NP_002991
Application

Western blot

Host: Rabbit Target Name: FAM46C Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNAS Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: NOP56 Sample Tissue: Human Fetal Muscle Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: HIRIP3 Sample Tissue: 293T Antibody Dilution: 1.0ug/ml

Western blot

Host: RabbitTarget Name: SERPINA3 Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: WT1 Sample Tissue: 721_B Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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