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MFNG antibody - C-terminal region

Catalog Number:OM113319
OM113319
Discount Price
OM113319-100ul
1~2 Week
100ul
OM113319-50ul
50ul
OM113319-20ul
20ul
1~2 Week
Product Profile
Product Name MFNG antibody - C-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-MFNG antibody: synthetic peptide directed towards the C terminal of human MFNG
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Rat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MFNG
Gene Synonyms -
Gene Full Name MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Gene Summary MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Molecular Weight(MW) 36kDa
Sequence 321 amino acids
Database Links
Entrez Gene 4242
SwissProt ID O00587
Protein Accession NP_002396
Application

Western blot

0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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