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Rabbit anti-OGT polyclonal antibody - N-terminal region

Catalog Number:OM113557
OM113557
Discount Price
OM113557-100ul
1~2 Week
100ul
OM113557-50ul
50ul
OM113557-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-OGT polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias FLJ23071, HRNT1, MGC22921, O-GLCNAC
Immunogen The immunogen for anti-OGT antibody: synthetic peptide directed towards the N terminal of human OGT
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePigRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol OGT
Gene Synonyms FLJ23071
HRNT1
MGC22921
O-GLCNAC
Gene Full Name O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Gene Summary OGT catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Names FLJ23071
HRNT1
MGC22921
O-GLCNAC
Molecular Weight(MW) 117kDa
Sequence 1046 amino acids
Database Links
Entrez Gene 8473
SwissProt ID O15294
Protein Accession NP_858058
Application

Western blot

Host: Rabbit Target Name: OGT Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: OGT Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: OGT Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: OGT Sample Tissue: Human Fetal Brain Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: OGT Sample Tissue: Jurkat Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: OGT Sample Tissue: HepG2 Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: OGT Sample Tissue: 721_B Whole Cell lysates Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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