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Rabbit anti-JPH3 polyclonal antibody - N-terminal region

Catalog Number:OM113695
OM113695
Discount Price
OM113695-100ul
1~2 Week
100ul
OM113695-50ul
50ul
OM113695-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-JPH3 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias CAGL237, FLJ44707, HDL2, JP-3, JP3, TNRC22
Immunogen The immunogen for anti-JPH3 antibody: synthetic peptide directed towards the N terminal of human JPH3
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol JPH3
Gene Synonyms CAGL237
FLJ44707
HDL2
JP-3
JP3
TNRC22
Gene Full Name Junctophilin 3
Gene Summary Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in the gene that encodes JPH3 protein. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names CAGL237
FLJ44707
HDL2
JP-3
JP3
TNRC22
Molecular Weight(MW) 81kDa
Sequence 748 amino acids
Database Links
Entrez Gene 57338
SwissProt ID Q8WXH2
Protein Accession NP_065706
Application

Western blot

0.2-1 ug/mlPositive Control: HepG2 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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