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Rabbit anti-GNPTAB polyclonal antibody - N-terminal region

Catalog Number:OM113819
OM113819
Discount Price
OM113819-100ul
1~2 Week
100ul
OM113819-50ul
50ul
OM113819-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-GNPTAB polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias DKFZp762B226, GNPTA, ICD, KIAA1208, MGC4170
Immunogen The immunogen for anti-GNPTAB antibody: synthetic peptide directed towards the N terminal of human GNPTAB
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMouseRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GNPTAB
Gene Synonyms DKFZp762B226
GNPTA
ICD
KIAA1208
MGC4170
Gene Full Name N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Gene Summary This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.
Alternative Names DKFZp762B226
GNPTA
ICD
KIAA1208
MGC4170
Molecular Weight(MW) 143kDa
Sequence 1256 amino acids
Database Links
Entrez Gene 79158
SwissProt ID Q3T906
Protein Accession NP_077288
Application

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: COLO205 Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: OVCAR-3 Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: NCI-H226 Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: ACHN Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: A549 Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNPTAB Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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