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Rabbit anti-WNT3 polyclonal antibody - middle region

Catalog Number:OM113882
OM113882
Discount Price
OM113882-100ul
1~2 Week
100ul
OM113882-50ul
50ul
OM113882-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-WNT3 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias INT4, MGC131950, MGC138321, MGC138323
Immunogen The immunogen for anti-WNT3 antibody: synthetic peptide directed towards the middle region of human WNT3
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogHorseHumanMousePigRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol WNT3
Gene Synonyms INT4
MGC131950
MGC138321
MGC138323
Gene Full Name Wingless-type MMTV integration site family, member 3
Gene Summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Alternative Names INT4
MGC131950
MGC138321
MGC138323
Molecular Weight(MW) 37kDa
Sequence 355 amino acids
Database Links
Entrez Gene 7473
SwissProt ID P56703
Protein Accession NP_110380
Application

Western blot

0.2-1 ug/mlPositive Control: Human brain
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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