Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate| Product Name | Rabbit anti-PYHIN1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IFIX, MGC23885, RP11-520H16.1 |
| Immunogen | The immunogen for anti-PYHIN1 antibody: synthetic peptide directed towards the N terminal of human PYHIN1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PYHIN1 |
|---|---|
| Gene Synonyms | IFIX MGC23885 RP11-520H16.1 |
| Gene Full Name | Pyrin and HIN domain family, member 1 |
| Gene Summary | PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. |
| Alternative Names | IFIX MGC23885 RP11-520H16.1 |
| Molecular Weight(MW) | 51kDa |
| Sequence | 452 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
