Western blot
Titration: 1.0 ug/mlPositive Control: Rat Heart| Product Name | Rabbit anti-Fxn polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RGD1565754, Fxn |
| Immunogen | The immunogen for anti-Fxn antibody: synthetic peptide corresponding to a region of Rat |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogGuinea PigHorseHumanMousePigRabbitZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Fxn |
|---|---|
| Gene Synonyms | RGD1565754 Fxn |
| Gene Full Name | Frataxin |
| Gene Summary | Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Fxn modulates the RNA-binding activity of ACO1. |
| Alternative Names | RGD1565754 Fxn |
| Molecular Weight(MW) | 23kDa |
| Sequence | 208 amino acids |
| Entrez Gene | 499335 |
|---|---|
| SwissProt ID | D3ZYW7 |
| Protein Accession | XP_001078791 |
Western blot
Titration: 1.0 ug/mlPositive Control: Rat Heart| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
