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Rabbit anti-COPA polyclonal antibody - middle region

Catalog Number:OM114577
OM114577
Discount Price
OM114577-100ul
1~2 Week
100ul
OM114577-50ul
50ul
OM114577-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-COPA polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias FLJ26320, HEP-COP
Immunogen The immunogen for anti-COPA antibody: synthetic peptide directed towards the middle region of human COPA
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol COPA
Gene Synonyms FLJ26320
HEP-COP
Gene Full Name Coatomer protein complex, subunit alpha
Gene Summary In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
Alternative Names FLJ26320
HEP-COP
Molecular Weight(MW) 135kDa
Sequence 1224 amino acids
Database Links
Entrez Gene 1314
SwissProt ID P53621
Protein Accession NP_004362
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 721_B cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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