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Rabbit anti-TXNIP polyclonal antibody - C-terminal region

Catalog Number:OM114713
OM114713
Discount Price
OM114713-100ul
1~2 Week
100ul
OM114713-50ul
50ul
OM114713-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-TXNIP polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias EST01027, HHCPA78, THIF, VDUP1
Immunogen The immunogen for anti-TXNIP antibody: synthetic peptide directed towards the C terminal of human TXNIP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TXNIP
Gene Synonyms EST01027
HHCPA78
THIF
VDUP1
Gene Full Name Thioredoxin interacting protein
Gene Summary TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Alternative Names EST01027
HHCPA78
THIF
VDUP1
Molecular Weight(MW) 44kDa
Sequence 391 amino acids
Database Links
Entrez Gene 10628
SwissProt ID Q9H3M7
Protein Accession NP_006463
Application

Western blot

Host: Rabbit Target Name: TXNIP Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: TXNIP Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/ml

Western blot

Lane 1: 20ug mouse mesenchymal stem cell lysate Primary Antibody Dilution : 1:2000 Secondary Antibody:Anti-rabbit-HRP Secondary Antibody Dilution: 1:10,000 Color/Signal Descriptions:TXNIP Gene Name:Anonymous Submitted by:

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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