Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Lung| Product Name | Rabbit anti-TXNIP polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EST01027, HHCPA78, THIF, VDUP1 |
| Immunogen | The immunogen for anti-TXNIP antibody: synthetic peptide directed towards the middle region of human TXNIP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TXNIP |
|---|---|
| Gene Synonyms | EST01027 HHCPA78 THIF VDUP1 |
| Gene Full Name | Thioredoxin interacting protein |
| Gene Summary | TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. |
| Alternative Names | EST01027 HHCPA78 THIF VDUP1 |
| Molecular Weight(MW) | 44kDa |
| Sequence | 391 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Lung| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
