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Rabbit anti-FBXW10 polyclonal antibody - N-terminal region

Catalog Number:OM114834
OM114834
Discount Price
OM114834-100ul
1~2 Week
100ul
OM114834-50ul
50ul
OM114834-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-FBXW10 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias Fbw10, HREP, SM25H2, SM2SH2
Immunogen The immunogen for anti-FBXW10 antibody: synthetic peptide directed towards the N terminal of human FBXW10
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol FBXW10
Gene Synonyms Fbw10
HREP
SM25H2
SM2SH2
Gene Full Name F-box and WD repeat domain containing 10
Gene Summary Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alternative Names Fbw10
HREP
SM25H2
SM2SH2
Molecular Weight(MW) 120kDa
Sequence 1051 amino acids
Database Links
Entrez Gene 10517
SwissProt ID Q5XX13
Protein Accession NP_113644
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Muscle
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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