Immunohistochemical
ImmunohistochemicalWestern blot
1 ug/mlPositive Control: 721_B cell lysate| Product Name | Rabbit anti-KLB polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BKL, MGC142213 |
| Immunogen | The immunogen for anti-KLB antibody: synthetic peptide directed towards the middle region of human KLB |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogGuinea PigHorseHumanRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KLB |
|---|---|
| Gene Synonyms | BKL MGC142213 |
| Gene Full Name | Klotho beta |
| Gene Summary | KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21. |
| Alternative Names | BKL MGC142213 |
| Molecular Weight(MW) | 120kDa |
| Sequence | 1044 amino acids |
Immunohistochemical
Immunohistochemical
Western blot
1 ug/mlPositive Control: 721_B cell lysate| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
