Western blot
0.2-1 ug/mlPositive Control: Jurkat cell lysateWestern blot
Host: Rabbit Target Name: CHMP4B Sample Tissue: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-CHMP4B polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C20orf178, CHMP4A, CTPP3, SNF7, SNF7-2, Shax1, dJ553F4.4, VPS32B, Vps32-2 |
| Immunogen | The immunogen for anti-CHMP4B antibody: synthetic peptide directed towards the middle region of human CHMP4B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorsePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CHMP4B |
|---|---|
| Gene Synonyms | C20orf178 CHMP4A CTPP3 SNF7 SNF7-2 Shax1 dJ553F4.4 VPS32B Vps32-2 |
| Gene Full Name | Charged multivesicular body protein 4B |
| Gene Summary | This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts. |
| Alternative Names | C20orf178 CHMP4A CTPP3 SNF7 SNF7-2 Shax1 dJ553F4.4 VPS32B Vps32-2 |
| Molecular Weight(MW) | 25kDa |
| Sequence | 224 amino acids |
Western blot
0.2-1 ug/mlPositive Control: Jurkat cell lysate
Western blot
Host: Rabbit Target Name: CHMP4B Sample Tissue: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
