Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate| Product Name | Rabbit anti-HFE2 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HFE2A, HJV, JH, MGC23953, RGMC |
| Immunogen | The immunogen for anti-HFE2 antibody: synthetic peptide directed towards the N terminal of human HFE2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHumanPigRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HFE2 |
|---|---|
| Gene Synonyms | HFE2A HJV JH MGC23953 RGMC |
| Gene Full Name | Hemochromatosis type 2 (juvenile) |
| Gene Summary | The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. |
| Alternative Names | HFE2A HJV JH MGC23953 RGMC |
| Molecular Weight(MW) | 21kDa |
| Sequence | 200 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
