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Rabbit anti-FGFR1OP polyclonal antibody - N-terminal region

Catalog Number:OM115426
OM115426
Discount Price
OM115426-100ul
1~2 Week
100ul
OM115426-50ul
50ul
OM115426-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-FGFR1OP polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias FOP
Immunogen The immunogen for anti-FGFR1OP antibody: synthetic peptide directed towards the N terminal of human FGFR1OP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol FGFR1OP
Gene Synonyms FOP
Gene Full Name FGFR1 oncogene partner
Gene Summary FGFR1OP is a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.
Alternative Names FOP
Molecular Weight(MW) 42kDa
Sequence 379 amino acids
Database Links
Entrez Gene 11116
SwissProt ID O95684
Protein Accession NP_919410
Application

Western blot

0.2-1 ug/mlPositive Control: Human Placenta
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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