Application
Antibody used in WB on Human Placenta at 0.2-1 ug/ml.Application
Antibody used in WB on Human Hela at 1 ug/ml.| Product Name | FGFR1OP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | FGFR1OP is a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6;8) (q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6;8) (q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.1) Mano, Y., (2007) Cancer Sci. 98 (12), 1902-1913. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGFR1OP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| FGFR1OP antibody can be used for detection of FGFR1OP by ELISA at 1:312500. FGFR1OP antibody can be used for detection of FGFR1OP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FGFR1OP |
|---|---|
| Alternative Names | FGFR1OP FOP |
| Molecular Weight(MW) | 42 kDa |
Application
Antibody used in WB on Human Placenta at 0.2-1 ug/ml.
Application
Antibody used in WB on Human Hela at 1 ug/ml.| Positive Control | 1) Cat. No. 1309 - Human Placenta Lysate |
|---|---|
| Application Notes | FGFR1OP antibody can be used for detection of FGFR1OP by ELISA at 1:312500. FGFR1OP antibody can be used for detection of FGFR1OP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store FGFR1OP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
