Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HT1080 cell lysate| Product Name | Rabbit anti-SPAG6 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp434I153, MGC26276, Repro-SA-1, pf16 |
| Immunogen | The immunogen for anti-SPAG6 antibody: synthetic peptide directed towards the middle region of human SPAG6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SPAG6 |
|---|---|
| Gene Synonyms | DKFZp434I153 MGC26276 Repro-SA-1 pf16 |
| Gene Full Name | Sperm associated antigen 6 |
| Gene Summary | SPAG6 is important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. |
| Alternative Names | DKFZp434I153 MGC26276 Repro-SA-1 pf16 |
| Molecular Weight(MW) | 56kDa |
| Sequence | 509 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HT1080 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
