Western blot
Titration: 1.0 ug/mlPositive Control: THP-1 Whole Cell| Product Name | Rabbit anti-APH1B polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APH-1B, DKFZp564D0372, FLJ33115, PRO1328, PSFL, TAAV688 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMouseRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | APH1B |
|---|---|
| Gene Synonyms | APH-1B DKFZp564D0372 FLJ33115 PRO1328 PSFL TAAV688 |
| Gene Full Name | Anterior pharynx defective 1 homolog B (C. elegans) |
| Gene Summary | This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. |
| Alternative Names | APH-1B DKFZp564D0372 FLJ33115 PRO1328 PSFL TAAV688 |
| Molecular Weight(MW) | 23kDa |
| Sequence | 216 amino acids |
| Entrez Gene | 83464 |
|---|---|
| SwissProt ID | Q564N3 |
| Protein Accession | NP_001139118 |
Western blot
Titration: 1.0 ug/mlPositive Control: THP-1 Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
