Western blot
0.2-1 ug/mlPositive Control: Human brain| Product Name | Rabbit anti-UBE4B polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | E4, HDNB1, KIAA0684, UBOX3, UFD2, UFD2A |
| Immunogen | The immunogen for anti-UBE4B antibody: synthetic peptide directed towards the N terminal of human UBE4B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogHumanPig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | UBE4B |
|---|---|
| Gene Synonyms | E4 HDNB1 KIAA0684 UBOX3 UFD2 UFD2A |
| Gene Full Name | Ubiquitination factor E4B |
| Gene Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Alternative Names | E4 HDNB1 KIAA0684 UBOX3 UFD2 UFD2A |
| Molecular Weight(MW) | 146kDa |
| Sequence | 1302 amino acids |
| Entrez Gene | 10277 |
|---|---|
| SwissProt ID | O95155 |
| Protein Accession | NP_001099032 |
Western blot
0.2-1 ug/mlPositive Control: Human brain| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
