Western blot
Titration: 1.0 ug/mlPositive Control: Rat Spleen| Product Name | Rabbit anti-Chmp2b Antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RGD1306781 |
| Immunogen | The immunogen for Anti-Chmp2b antibody is: synthetic peptide directed towards the N-terminal region of Rat Chmp2b |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | RatHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Chmp2b |
|---|---|
| Gene Synonyms | RGD1306781 |
| Gene Summary | Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis . |
| Alternative Names | RGD1306781 |
| Molecular Weight(MW) | 23kDa |
| Sequence | 213 amino acids |
| Entrez Gene | 363720 |
|---|---|
| Protein Accession | XP_001063932 |
Western blot
Titration: 1.0 ug/mlPositive Control: Rat Spleen| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
