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Rabbit anti-RHOC polyclonal antibody - N-terminal region

Catalog Number:OM116267
OM116267
Discount Price
OM116267-100ul
1~2 Week
100ul
OM116267-50ul
50ul
OM116267-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-RHOC polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias ARH9, ARHC, H9, MGC1448, MGC61427, RHOH9
Immunogen The immunogen for anti-RHOC antibody: synthetic peptide directed towards the N terminal of human RHOC
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineHumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol RHOC
Gene Synonyms ARH9
ARHC
H9
MGC1448
MGC61427
RHOH9
Gene Full Name Ras homolog family member C
Gene Summary RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternative Names ARH9
ARHC
H9
MGC1448
MGC61427
RHOH9
Molecular Weight(MW) 22kDa
Sequence 193 amino acids
Database Links
Entrez Gene 389
SwissProt ID P08134
Protein Accession NP_786886
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Live
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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