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Rabbit anti-FBXO33 polyclonal antibody - middle region

Catalog Number:OM116381
OM116381
Discount Price
OM116381-100ul
1~2 Week
100ul
OM116381-50ul
50ul
OM116381-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-FBXO33 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias Fbx33, c14_5247, BMND12
Immunogen The immunogen for anti-FBXO33 antibody: synthetic peptide directed towards the middle region of human FBXO33
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseMouseRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol FBXO33
Gene Synonyms Fbx33
c14_5247
BMND12
Gene Full Name F-box protein 33
Gene Summary FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alternative Names Fbx33
c14_5247
BMND12
Molecular Weight(MW) 62kDa
Sequence 555 amino acids
Database Links
Entrez Gene 254170
SwissProt ID Q7Z6M2
Protein Accession NP_976046
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Live
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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