Western blot
Host: Rabbit Target Name: TESC Sample Tissue: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-TESC Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CHP3, TSC |
| Immunogen | The immunogen for Anti-TESC antibody is: synthetic peptide directed towards the C-terminal region of Human TESC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TESC |
|---|---|
| Gene Synonyms | CHP3 TSC |
| Gene Full Name | tescalcin |
| Gene Summary | TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane and promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner and inhibits the phosphatase activity of calcineurin. |
| Alternative Names | CHP3 TSC |
| Molecular Weight(MW) | 23kDa |
| Sequence | 214 amino acids |
Western blot
Host: Rabbit Target Name: TESC Sample Tissue: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
