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Rabbit anti-PLAT polyclonal antibody - middle region

Catalog Number:OM117276
OM117276
Discount Price
OM117276-100ul
1~2 Week
100ul
OM117276-50ul
50ul
OM117276-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-PLAT polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias DKFZp686I03148, T-PA, TPA
Immunogen The immunogen for anti-PLAT antibody: synthetic peptide directed towards the middle region of human PLAT
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogGuinea PigHorseHumanPigRabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PLAT
Gene Synonyms DKFZp686I03148
T-PA
TPA
Gene Full Name Plasminogen activator, tissue
Gene Summary This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alternative Names DKFZp686I03148
T-PA
TPA
Molecular Weight(MW) 53kDa
Sequence 516 amino acids
Database Links
Entrez Gene 5327
SwissProt ID P00750-3
Protein Accession NP_127509
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: PANC1 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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