Western blot
0.2-1 ug/mlPositive Control: 293T cell lysate| Product Name | Rabbit anti-WDR77 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HKMT1069, MEP50, MGC2722, Nbla10071, RP11-552M11.3, p44, MEP-50, p44/Mep50 |
| Immunogen | The immunogen for anti-WDR77 antibody: synthetic peptide directed towards the N terminal of human WDR77 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | WDR77 |
|---|---|
| Gene Synonyms | HKMT1069 MEP50 MGC2722 Nbla10071 RP11-552M11.3 p44 MEP-50 p44/Mep50 |
| Gene Full Name | WD repeat domain 77 |
| Gene Summary | WDR77 is the non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. WDR77 might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. |
| Alternative Names | HKMT1069 MEP50 MGC2722 Nbla10071 RP11-552M11.3 p44 MEP-50 p44/Mep50 |
| Molecular Weight(MW) | 38kDa |
| Sequence | 342 amino acids |
Western blot
0.2-1 ug/mlPositive Control: 293T cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
