Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate| Product Name | Rabbit anti-SHB polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RP11-3J10.8, bA3J10.2 |
| Immunogen | The immunogen for anti-SHB antibody: synthetic peptide directed towards the N terminal of human SHB |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHumanMouseRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SHB |
|---|---|
| Gene Synonyms | RP11-3J10.8 bA3J10.2 |
| Gene Full Name | Src homology 2 domain containing adaptor protein B |
| Gene Summary | SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells. |
| Alternative Names | RP11-3J10.8 bA3J10.2 |
| Molecular Weight(MW) | 55kDa |
| Sequence | 509 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
