Western blot
Host: Rabbit Target Name: Arhgef4 Sample Tissue: Mouse Testis lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-Arhgef4 Antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 9330140K16Rik, Asef, ENSMUSG00000070955 |
| Immunogen | The immunogen for Anti-Arhgef4 antibody is: synthetic peptide directed towards the N-terminal region of Mouse Arhgef4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Arhgef4 |
|---|---|
| Gene Synonyms | 9330140K16Rik Asef ENSMUSG00000070955 |
| Gene Full Name | Rho guanine nucleotide exchange factor (GEF) 4 |
| Gene Summary | Arhgef4 acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion By similarity. It is required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Arhgef4 is involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. |
| Alternative Names | 9330140K16Rik Asef ENSMUSG00000070955 |
| Molecular Weight(MW) | 57kDa |
| Sequence | 484 amino acids |
Western blot
Host: Rabbit Target Name: Arhgef4 Sample Tissue: Mouse Testis lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
