Western blot
Titration: 1.0 ug/mlPositive Control: Mouse Heart| Product Name | Rabbit anti-Rnls polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 6530404N21Rik, AI452315, AW060440, C10orf59 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Guinea PigHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Rnls |
|---|---|
| Gene Synonyms | 6530404N21Rik AI452315 AW060440 C10orf59 |
| Gene Full Name | Renalase, FAD-dependent amine oxidase |
| Gene Summary | Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. |
| Alternative Names | 6530404N21Rik AI452315 AW060440 C10orf59 |
| Molecular Weight(MW) | 33kDa |
| Sequence | 300 amino acids |
| Entrez Gene | 67795 |
|---|---|
| SwissProt ID | A7RDN6 |
| Protein Accession | NP_001161290 |
Western blot
Titration: 1.0 ug/mlPositive Control: Mouse Heart| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
