Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: ACHN cell lysate| Product Name | Rabbit anti-BTBD12 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIAA1784, KIAA1987, MUS312, SLX4, FANCP, BTBD12 |
| Immunogen | The immunogen for anti-BTBD12 antibody: synthetic peptide directed towards the N terminal of human BTBD12 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BTBD12 |
|---|---|
| Gene Synonyms | KIAA1784 KIAA1987 MUS312 SLX4 FANCP BTBD12 |
| Gene Full Name | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) |
| Gene Summary | This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases. |
| Alternative Names | KIAA1784 KIAA1987 MUS312 SLX4 FANCP BTBD12 |
| Molecular Weight(MW) | 200kDa |
| Sequence | 1834 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: ACHN cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
