Western blot
0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Hela cell lysate| Product Name | Rabbit anti-MRGPRX2 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MRGX2 |
| Immunogen | The immunogen for anti-MRGPRX2 antibody: synthetic peptide directed towards the middle region of human MRGPRX2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MRGPRX2 |
|---|---|
| Gene Synonyms | MRGX2 |
| Gene Full Name | MAS-related GPR, member X2 |
| Gene Summary | MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. |
| Alternative Names | MRGX2 |
| Molecular Weight(MW) | 37kDa |
| Sequence | 330 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Hela cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
