Application
MRGPRX2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MRGPRX2 antibody detected the MRGPRX2 protein (arrow).| Product Name | MRGPRX2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MRGX2 |
|---|---|
| Alternative Names | MRGPRX2 MRGX2 Mas-related G-protein coupled receptor member X2 |
| Molecular Weight(MW) | 37099 Da |
| Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain Cortistatin-14 seems to be a high potency ligand at this receptor Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin- stimulated cAMP levels, suggesting that this receptor is G(q)- coupled |
| Tissue Specificity | Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 117194 |
|---|---|
| Nucleotide Accession | NP_473371.1 |
Application
MRGPRX2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MRGPRX2 antibody detected the MRGPRX2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
