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Rabbit anti-FGFR2 polyclonal antibody - middle region
Catalog Number:OM118315
OM118315
Discount Price
OM118315-100ul
1~2 Week
100ul
OM118315-50ul
50ul
OM118315-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-FGFR2 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FLJ98662, JWS, K-SAM, KGFR, TK14, TK25
Immunogen The immunogen for anti-FGFR2 antibody: synthetic peptide directed towards the middle region of human FGFR2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRatSheepZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol FGFR2
Gene Synonyms BEK
BFR-1
CD332
CEK3
CFD1
ECT1
FLJ98662
JWS
K-SAM
KGFR
TK14
TK25
Gene Full Name Fibroblast growth factor receptor 2
Gene Summary The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alternative Names BEK
BFR-1
CD332
CEK3
CFD1
ECT1
FLJ98662
JWS
K-SAM
KGFR
TK14
TK25
Molecular Weight(MW) 78kDa
Sequence 705 amino acids
Database Links
Entrez Gene 2263
SwissProt ID P21802
Protein Accession NP_075259
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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