Western blot
Titration: 1.0 ug/mlPositive Control: 721_B Whole Cell| Product Name | Rabbit anti-ST5 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DENND2B, HTS1, MGC33090, p126 |
| Immunogen | The immunogen for anti-ST5 antibody: synthetic peptide directed towards the middle region of human ST5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ST5 |
|---|---|
| Gene Synonyms | DENND2B HTS1 MGC33090 p126 |
| Gene Full Name | Suppression of tumorigenicity 5 |
| Gene Summary | This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. |
| Alternative Names | DENND2B HTS1 MGC33090 p126 |
| Molecular Weight(MW) | 126kDa |
| Sequence | 1137 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: 721_B Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
