Western blot
Host: Rabbit Target Name: Wibg Sample Tissue: Mouse Thymus lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-Wibg Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | A030010B05Rik, Pym |
| Immunogen | The immunogen for Anti-Wibg antibody is: synthetic peptide directed towards the middle region of Mouse Wibg |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | MouseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Wibg |
|---|---|
| Gene Synonyms | A030010B05Rik Pym |
| Gene Full Name | within bgcn homolog (Drosophila) |
| Gene Summary | Wibg is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. It acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Wibg interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. |
| Alternative Names | A030010B05Rik Pym |
| Molecular Weight(MW) | 22kDa |
| Sequence | 202 amino acids |
| Entrez Gene | 78428 |
|---|---|
| Protein Accession | NP_001164340 |
Western blot
Host: Rabbit Target Name: Wibg Sample Tissue: Mouse Thymus lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
