Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Kidney| Product Name | Rabbit anti-EDN3 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ET3, MGC15067, MGC61498, ET-3, WS4B, HSCR4, PPET3 |
| Immunogen | The immunogen for anti-EDN3 antibody: synthetic peptide directed towards the C terminal of human EDN3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanPig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EDN3 |
|---|---|
| Gene Synonyms | ET3 MGC15067 MGC61498 ET-3 WS4B HSCR4 PPET3 |
| Gene Full Name | Endothelin 3 |
| Gene Summary | The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. |
| Alternative Names | ET3 MGC15067 MGC61498 ET-3 WS4B HSCR4 PPET3 |
| Molecular Weight(MW) | 24kDa |
| Sequence | 219 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Kidney| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
