Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Lung| Product Name | Rabbit anti-ZAP70 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70 |
| Immunogen | The immunogen for anti-ZAP70 antibody: synthetic peptide directed towards the N terminal of human ZAP70 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineGuinea PigHumanMousePigRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZAP70 |
|---|---|
| Gene Synonyms | FLJ17670 FLJ17679 SRK STD TZK ZAP-70 |
| Gene Full Name | Zeta-chain (TCR) associated protein kinase 70kDa |
| Gene Summary | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
| Alternative Names | FLJ17670 FLJ17679 SRK STD TZK ZAP-70 |
| Molecular Weight(MW) | 34kDa |
| Sequence | 312 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Lung| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
