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Rabbit anti-SOCS2 polyclonal antibody - C-terminal region

Catalog Number:OM119574
OM119574
Discount Price
OM119574-100ul
1~2 Week
100ul
OM119574-50ul
50ul
OM119574-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-SOCS2 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SOCS2
Gene Synonyms CIS2
Cish2
SOCS-2
SSI-2
SSI2
STATI2
Gene Full Name Suppressor of cytokine signaling 2
Gene Summary This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.
Alternative Names CIS2
Cish2
SOCS-2
SSI-2
SSI2
STATI2
Molecular Weight(MW) 22kDa
Sequence 198 amino acids
Database Links
Entrez Gene 8835
SwissProt ID O14508
Protein Accession NP_003868
Application

Immunoblot

Lane 1: 50ug Mouse adipose lysatePrimary Antibody Dilution: 1:1000Secondary Antibody: Donkey anti-Rabbit-HRPSecondary Antibody Dilution: 1:10000Gene Name: SOCS2Submitted by: Libin Liu, Boston University.

Western blot

Titration: 1.0 ug/mlPositive Control: U937 Whole Cell
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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