Western blot
Titration: 1.0 ug/mlPositive Control: 293T Whole Cell| Product Name | Rabbit anti-PDE6B polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CSNB3, CSNBAD2, PDEB, RP40, rd1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDE6B |
|---|---|
| Gene Synonyms | CSNB3 CSNBAD2 PDEB RP40 rd1 |
| Gene Full Name | Phosphodiesterase 6B, cGMP-specific, rod, beta |
| Gene Summary | Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | CSNB3 CSNBAD2 PDEB RP40 rd1 |
| Molecular Weight(MW) | 98kDa |
| Sequence | 854 amino acids |
| Entrez Gene | 5158 |
|---|---|
| SwissProt ID | E7ETT3 |
| Protein Accession | NP_001138764 |
Western blot
Titration: 1.0 ug/mlPositive Control: 293T Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
