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Rabbit anti-WISP2 polyclonal antibody - C-terminal region

Catalog Number:OM119853
OM119853
Discount Price
OM119853-100ul
1~2 Week
100ul
OM119853-50ul
50ul
OM119853-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-WISP2 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias CCN5, CT58, CTGF-L
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol WISP2
Gene Synonyms CCN5
CT58
CTGF-L
Gene Full Name WNT1 inducible signaling pathway protein 2
Gene Summary This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Alternative Names CCN5
CT58
CTGF-L
Molecular Weight(MW) 24kDa
Sequence 250 amino acids
Database Links
Entrez Gene 8839
SwissProt ID O76076
Protein Accession NP_003872
Application

Western blot

RabbitTarget Name: WISP2Antibody Dilution: 1.0ug/mlSample Tissue: Human Placenta

Western blot

HeLa
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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