Western blot
Titration: 1.0 ug/mlPositive Control: COLO205 Whole Cell| Product Name | Rabbit anti-CYFIP1 Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ45151, P140SRA-1, SHYC, SRA1 |
| Immunogen | The immunogen for Anti-CYFIP1 antibody is: synthetic peptide directed towards the C-terminal region of Human CYFIP1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CYFIP1 |
|---|---|
| Gene Synonyms | FLJ45151 P140SRA-1 SHYC SRA1 |
| Gene Full Name | Cytoplasmic FMR1 interacting protein 1 |
| Gene Summary | CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers. |
| Alternative Names | FLJ45151 P140SRA-1 SHYC SRA1 |
| Molecular Weight(MW) | 145kDa |
| Sequence | 1253 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: COLO205 Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
