Western blot
Titration: 1.0 ug/mlPositive Control: 293T Whole Cell| Product Name | Rabbit anti-C8orf4 Antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGC22806, TC-1, TC1, hTC-1 |
| Immunogen | The immunogen for Anti-C8orf4 antibody is: synthetic peptide directed towards the N-terminal region of Human C8orf4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | C8orf4 |
|---|---|
| Gene Synonyms | MGC22806 TC-1 TC1 hTC-1 |
| Gene Full Name | Chromosome 8 open reading frame 4 |
| Gene Summary | This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. |
| Alternative Names | MGC22806 TC-1 TC1 hTC-1 |
| Molecular Weight(MW) | 12kDa |
| Sequence | 106 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: 293T Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
