| Product Name | Rabbit anti-RDH8 Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PRRDH, SDR28C2 |
| Immunogen | The immunogen for Anti-RDH8 antibody is: synthetic peptide directed towards the middle region of Human RDH8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RDH8 |
|---|---|
| Gene Synonyms | PRRDH SDR28C2 |
| Gene Full Name | Retinol dehydrogenase 8 (all-trans) |
| Gene Summary | All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors; hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin. |
| Alternative Names | PRRDH SDR28C2 |
| Molecular Weight(MW) | 34kDa |
| Sequence | 311 amino acids |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
