| Product Name | Rabbit anti-IPO8 Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ26580, RANBP8 |
| Immunogen | The immunogen for Anti-IPO8 antibody is: synthetic peptide directed towards the C-terminal region of Human IPO8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IPO8 |
|---|---|
| Gene Synonyms | FLJ26580 RANBP8 |
| Gene Full Name | Importin 8 |
| Gene Summary | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | FLJ26580 RANBP8 |
| Molecular Weight(MW) | 96kDa |
| Sequence | 832 amino acids |
| Entrez Gene | 10526 |
|---|---|
| SwissProt ID | O15397 |
| Protein Accession | NP_001177924 |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
