| Product Name | FBXL15 Antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for Anti-FBXL15 antibody is: synthetic peptide directed towards the N-terminal region of Human FBXL15 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FBXL15 |
|---|---|
| Gene Synonyms | FBXO37 Fbl15 JET PSD |
| Gene Summary | FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2. |
| Alternative Names | FBXO37 Fbl15 JET PSD |
| Molecular Weight(MW) | 32kDa |
| Sequence | 300 amino acids |
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
