Application
FBXL15 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL15 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Western blot analysis of FBXL15 Antibody (C-term) (RB26324) in MDA-MB435 cell line lysates (35ug/lane).FBXL15 (arrow) was detected using the purified Pab.Application
Western blot analysis of FBXL15 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane).FBXL15 (arrow) was detected using the purified Pab.| Product Name | FBXL15 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~100 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FBXO37 |
|---|---|
| Alternative Names | FBXL15 FBXO37 F-box/LRR-repeat protein 15 F-box only protein 37 |
| Molecular Weight(MW) | 32998 Da |
| Function | Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2 |
| Tissue Specificity | This FBXL15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-290 amino acids from the C-terminal region of human FBXL15. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 79176 |
|---|
Application
FBXL15 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL15 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Western blot analysis of FBXL15 Antibody (C-term) (RB26324) in MDA-MB435 cell line lysates (35ug/lane).FBXL15 (arrow) was detected using the purified Pab.
Application
Western blot analysis of FBXL15 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane).FBXL15 (arrow) was detected using the purified Pab.| Application Notes | IHC:1:50~100 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
