| Gene Symbol |
CCL18
|
| Gene Synonyms |
CKb7 PARC AMAC1 DCCK1 MIP-4 AMAC-1 DC-CK1 SCYA18 |
| Gene Full Name |
Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| Gene Summary |
CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. |
| Alternative Names |
CKb7 PARC AMAC1 DCCK1 MIP-4 AMAC-1 DC-CK1 SCYA18 |
| Molecular Weight(MW) |
10kDa |
| Sequence |
89 amino acids |