Application
Western blot analysis of human recombinant IFN-α fusion protein.| Product Name | IFN-α Antibody (FL-189) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-189 representing full length IFN-α13 of human origin |
| Modification Notes | The genes encoding type I interferons (IFNs), which include 14 IFN-å genes, 1 IFN-∫ gene, 1 IFN-w (also known as IFN-å II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferon-å and -∫ are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-å, IFN-∫ or IFN-©, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-åR) interacts with IFN-å, IFN-∫ and IFN-w, and seems to be a multisubunit receptor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IFN-α1 and 13, and to a lesser extent IFN-α5, 6, 14 and 21 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-189 representing full length IFN-&alpha 13 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-189 representing full length IFN-α13 of human origin |
| Entrez Gene | 3439 |
|---|
Application
Western blot analysis of human recombinant IFN-α fusion protein.| Application Notes | recommended for detection of IFN-α1 and 13, and to a lesser extent IFN-α5, 6, 14 and 21 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
