Application
Western blot analysis of JFC1 expression in non-transfected: (A) and human JFC1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of JFC1 expression in non-transfected: (A) and human JFC1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of JFC1 expression in non-transfected: (A) and human JFC1 transfected: (B) 293T whole cell lysates.| Product Name | JFC1 Antibody (H-80) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 471-550 mapping at the C-terminus of JFC1 of human origin |
| Modification Notes | Synaptotagmins, rabphilin-3A and DOC2 belong to a family of C-terminal type (C-type) tandem C2 proteins and are involved in vesicular trafficking. JFC1, also designated Slp1 (for synaptotagmin-like protein), belong to a unique family of C-type tandem C2 proteins designated Slp. JFC1 contains two N-terminal Slp homology comains (SHD), which each comprise two conserved å-helical regions, desigated SHD1 and SHD2. SHD1 and SHD2 specifically and directly bind the GTP-bound form of Rab 27a. JFC1 also binds phosphatidylinositol 3,4,5-triphosphate-binding ATPase. JFC1 is transcriptionally activated by Nf˚B and upregulated by TNFå in prostate carcinoma cells. JFC1 associates with the plasma membrane. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of JFC1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 471-550 mapping at the C-terminus of JFC1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 471-550 mapping at the C-terminus of JFC1 of human origin |
| Entrez Gene | 84958 |
|---|
Application
Western blot analysis of JFC1 expression in non-transfected: (A) and human JFC1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of JFC1 expression in non-transfected: (A) and human JFC1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of JFC1 expression in non-transfected: (A) and human JFC1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of JFC1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
